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Cases done
by Gynecologists


Ectopic calcification


Ectopic calcification refers to a condition in which damage is caused to soft tissues due to deposition of calcium salts causing bone growth.

Ectopic calcification is considered as an important clinical manifestation of hyperphosphatemia. [1]

- Requires medical diagnosis
- Treatable by a medical professional depending on the severity
- Lab tests or imaging may be required
Through calcification, the damage may occur in vessels, heart valves, lungs, kidney, and brain. The risk increases with age. Brain calcification is associated with health conditions such as Down's syndrome, Lewy body disease, Alzheimer's disease, and brain tumors.
The cause of calcification can be metabolic and inflammatory disorders, sometimes also genetic predisposition.


- Formation of firm lumps underneath the skin surface
- Some of the lumps may be painful
- Lumps may ulcerate the skin
- Limited motion of a joint


The underlying cause of the ectopic calcification is identified and treated accordingly. Some calcifications don't require treatment and resolve on their own.
Calcification in cardiovascular tissue resulting in aortic stenosis can be treated by aortic valve replacement.

In the case of calcification resulting in hyperphosphatemia, the treatment is accomplished by administration of acetazolamide apart from the dietary restriction of phosphate and oral phosphate binders.

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