Gamma-Glutamyl Transpeptidase (GGT) SerumDr. Sreelekha DaruvuriLast Updated on 21st March 2022
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What is Gamma-Glutamyl Transpeptidase (GGT) Serum test used for?
Your liver is essential for protein metabolism and toxin removal in your body. It also produces bile, a chemical that aids your body’s fat digestion.
If your doctor suspects that your liver is damaged or that you have liver disease, especially related to alcohol consumption, he or she may order the GGT test. Currently, the GGT test is one of the most sensitive enzymatic indicators of liver damage and illness. This harm is frequently caused by excessive use of alcohol or other hazardous substances such as drugs or toxins.
This test is used
– To diagnose liver or bile duct disorders
– In conjunction with other tests (such as the ALT, AST, ALP, and bilirubin tests) to distinguish between liver and bile duct problems and bone disease.
– To screen for or track alcohol consumption.
What is included in the Gamma-Glutamyl Transpeptidase (GGT) Serum test?
A Gamma-Glutamyl Transpeptidase (GGT) Serum test measures GGT levels in the bloodstream. GGT is an enzyme that can be found in multiple parts of the body, although it is predominantly derived from the liver.
Procedure for Gamma-Glutamyl Transpeptidase (GGT) Serum test
The GGT test is a simple blood test.
– A band will be tied around the upper arm, an alcohol pad will be used to wipe the inner elbow, and a tiny needle will be inserted into the skin. Then, they will draw blood from a tiny tube.
– Following the test, the needle will be removed, and pressure will be applied to the location to ensure that any bleeding ceases.
– Like any other blood test, the blood draw may produce modest, brief discomfort that will disappear soon.
– The sample will be labelled and sent to a lab for testing by the healthcare expert. The lab should have the results within a day or two, though the doctor may need to wait longer to obtain and interpret them.
How to prepare for Gamma-Glutamyl Transpeptidase (GGT) Serum test?
You may be asked to fast (nothing to eat or drink except water) for at least 8 hours before the test. You may also be asked to discontinue the use of alcohol or certain prescribed drugs.
Things to consider after Gamma-Glutamyl Transpeptidase (GGT) Serum test is complete
Liver injury is serious and frequently leads to other health issues. It may also be irreparable, depending on the extent of the damage. The GGT test, when combined with other testing methods, can assist your doctor in determining whether you have liver impairment.
Consult your doctor if you have any signs of liver damage so that they can test you, determine the cause, and get you started on a treatment plan.
According to research, heavy coffee consumers may have reduced GGT levels, although it may take more than five cups per day. However, be aware that excessive coffee consumption has issues, such as high blood pressure and difficulty sleeping.
Finally, quitting smoking, abstaining from alcohol, and decreasing weight are critical first steps toward lowering GGT levels and allowing the liver to repair while leading a healthier lifestyle.
If you have any concerns about your results, speak with your doctor.
What types of infection can the Gamma-Glutamyl Transpeptidase (GGT) Serum test detect?
Gamma-Glutamyl Transpeptidase Serum test does not detect any infections. But it indicates liver injury and is used in diagnosing Hepatitis infection
How much does the Gamma-Glutamyl Transpeptidase (GGT) Serum test cost?
A Gamma – Glutamyl Transpeptidase (GGT) Serum test can cost anywhere between Rs.150 to Rs. 500 depending on your location.
*Disclaimer: The value varies based on location, time, and your preferred lab partner.
How long does it take to get the results for the Gamma-Glutamyl Transpeptidase (GGT) Serum test?
You can expect to get the Gamma-Glutamyl Transpeptidase (GGT) Serum test results within 24 to 48 hours after the sample is collected. However, in certain cases, depending on the location, medical advice, and preferred lab partner, it may take longer.
What do abnormal Gamma-Glutamyl Transpeptidase (GGT) Serum test results indicate?
The typical range for Gamma-Glutamyl transferase (GGT) differs between laboratories. Adults typically have a reference range of 5 to 40 U/L. (units per litre). Because ranges might differ depending on the laboratory, it’s critical to review your test result report to determine your lab’s reference range.
It’s worth noting that GGT levels are slightly greater in men .If your GGT test results are low or normal, you are unlikely to have liver disease.
If your GGT levels are greater than normal, this could be a symptom of liver injury. One of the following conditions could be causing the damage:
- An alcoholism disorder
- Heart failure with congestive edema
- A drug’s side effects.
Disclaimer: Please consult with your doctor to interpret the test reports.
Is Gamma-Glutamyl Transpeptidase (GGT) Serum a definitive test?
Serum Gamma-Glutamyl Transpeptidase (GGT) is a low-cost, highly sensitive, dependable laboratory test used to detect hepatobiliary dysfunction and alcohol misuse.
However, it is administered with other serum tests such as ALP for more accurate findings.
How to read the Gamma-Glutamyl Transpeptidase (GGT) Serum report?
The GGT results are evaluated in conjunction with the ALP values and any other tests that may have been run simultaneously, such as a liver panel.
A high GGT level in conjunction with an elevated ALP level helps rule out bone disease as the source of the elevated ALP level. Conversely, an elevated ALP with a low or normal GGT indicates that the elevated ALP is most likely caused by bone disease.
An increased GGT level indicates that a condition or disease is causing liver damage but does not specify the reason. In general, the higher the level, the bigger the liver damage. Liver illnesses like hepatitis or cirrhosis can cause elevated levels. Still, they can also be caused by other conditions such as congestive heart failure, metabolic syndrome, diabetes, pancreatitis, an infection of the pancreas. They can also be caused by alcoholism, alcoholic liver disease, or the use of toxic medicines which can cause damage to the liver.
NORMAL GGT LEVELS
|Age (Months/Years)||Males (units per liter)||Females (units per liter)|
|0-6 Months||12-122 U/L||15-132 U/L|
|6 Months – 1 Year||1-39 U/L||1-39 U/L|
|1-12 Years||3-22 U/L||3-22 U/L|
|13-18 Years||2-42 U/L||4-24 U/L|
|18-30 Years||9-43 U/L||8-35 U/L|
|30-50 Years||9-72 U/L||7-40 U/L|
|50-70 Years||10-87 U/L||7-56 U/L|
|>70 Years||8-69 U/L||8-55 U/L|
A low or normal GGT test result suggests that you do not have liver disease and have not ingested any alcohol.
Why book Gamma-Glutamyl Transpeptidase (GGT) Serum test?
The Gamma-Glutamyl Transpeptidase test is required to diagnose any liver or bile duct disorder in the body. The GGT test can also help in distinguishing between liver and bone illnesses as potential causes of increased alkaline phosphatase levels (ALP). A doctor may recommend the Gamma–GGT test if he suspects liver damage or disease due to alcohol consumption. The Gamma–GGT test can monitor GGT levels in persons who are being treated for alcoholic hepatitis. The following are some of the signs of a liver disorder:
- Reduced Appetite
- Vomiting or nausea
- Tiredness and a lack of energy
- Pain in the abdomen
- Itching of skin
- Dark Urine
Gamma-Glutamyl Transpeptidase (GGT) Serum test at home – how does it work?
The Gamma – Glutamyl Transpeptidase (GGT) Serum test is just like any other blood test. A lab technician visits your home when you book your tests through the MFine app. The lab technician first cleans the arm and then inserts a syringe into a vein. The required amount of blood is then taken into a vial. The lab technician then removes the needle and places cotton wool or a bandage over the prick.
Are there any risks involved with Gamma-Glutamyl Transpeptidase (GGT) Serum?
A blood draw is a very safe practice. However, following the test, some persons have to bruise at the needle insertion site. It is also typical to be sore for a brief period of time after the test.
A person may occasionally feel faint or anxious throughout the test, causing them to blackout or faint. Though worrisome, this does not signal a dangerous reaction.
What can affect the results for Gamma-Glutamyl Transpeptidase (GGT) Serum?
– Barbiturates, phenobarbital, and several over-the-counter medications can raise GGT levels in the body. GGT levels rise with age in women but not in males.
– Even tiny amounts of alcohol consumed within 24 hours of a GGT test can result in a temporary elevation in GGT. However, genetic variances between individuals can result in differences in GGT response to alcohol usage.
– GGT can also be increased by smoking.
– GGT levels that are elevated may be a sign of cardiovascular disease and/or hypertension.
– Patients with higher GGT levels have a higher chance of dying from heart disease, although this explanation is unknown.
– If you have recently quit drinking heavily, it can take up to a month for your GGT to return to normal.
For further assistance
Frequently Asked Questions | FAQs
Is the lab technician coming for Gamma-Glutamyl Transpeptidase (GGT) Serum sample collection vaccinated?
Yes. Our lab technicians are fully vaccinated. Further, they also ensure safety by wearing masks and gloves and frequently sanitising themselves during sample collection.
Does MFine provide the interpretation for the results along with the reports?
Yes, MFine provides the interpretation for the result along with the reports. You can also avail a free medical consultation with a doctor to understand your reports accurately. The doctor will also advise and prescribe medicines, if required, based on the results
How can I download my Gamma-Glutamyl Transpeptidase (GGT) Serum test report?
- Login to MFine
- Go to your profile
- Click on Attachment and Reports
- Click on Lab Report
- Download the report
Are there any discount offers running on Gamma-Glutamyl Transpeptidase (GGT) Serum test?
Usually, you can avail yourself upto a 50% discount on Gamma-Glutamyl Transpeptidase (GGT) Serum through MFine. However, the discount and test price may vary based on lab partner and location.
Should I be concerned if my GGT is elevated?
A higher-than-normal GGT level in your blood may indicate that a condition or disease harms your liver. The GGT test, on the other hand, cannot pinpoint the exact cause of the injury. In general, the higher your GGT level, the more damage your liver will sustain.
Is a high GGT level indicative of a fatty liver?
GGT levels that are frequently increased can be considered a significant contributor to fatty liver alterations. Elevated GGT in non-drinkers can occasionally be used as a proxy measure for fatty liver. According to the data, repeatedly increased GGT levels are a good predictor of fatty liver alterations.
What foods should you avoid if you have elevated liver enzymes?
If you have fatty liver disease, there are six foods you should avoid.
- Alcohol: Alcohol can majorly contribute to fatty liver disease and other liver illnesses.
- Extra sugar: Avoid sugary meals like sweets, cookies, sodas, and fruit juices.
- Fried food
- Extra salt
- Red Meat
Is it necessary to fast before taking the GGT blood test?
Your doctor may advise you to fast for eight hours before the test and discontinue certain medications. Even a modest amount of alcohol consumed within 24 hours of the test can impact your findings.
Is it possible for my GGT level to be raised if I don't have any symptoms?
Yes, GGT is quite sensitive and can rise even with no symptoms. This rise could be transitory due to medications you’re taking or drinking alcohol within 24 hours of the test. If your other liver enzymes are normal, your doctor may decide to repeat the GGT test at a later time. If your GGT is very high and/or your other liver enzymes are excessive, you may need more testing to determine the cause.
I used to be an alcoholic, but I've stopped drinking. Will my GGT ever be normal again?
Your GGT level will gradually decrease from whatever it was when you stopped consuming alcohol to within the usual range. This can take anywhere from a few weeks to more than a month. Abstinence from alcohol will reduce your chances of further liver damage and should allow your liver function to improve.