U1-nRNP Antibodies

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Overview Brief

Wishing to be well-informed before going for U1-nRNP Antibodies test? In this article you will read about the basics of this test, parameters measured, risks, preparations and post care after U1-nRNP Antibodies test.

What is U1-nRNP Antibodies test?

High levels of antibodies to ribonucleoprotein(RNP) also called U1-nRNP Antibodies, are found in patients having various systemic rheumatic diseases. About 50% of patients with lupus erythematosus,or connective tissue diseases or mixed connective tissue diseases show U1-nRNP Antibodies.[1] The U1-nRNP Antibodies test is an ELISA based blood-test, i.e a plate-based assay technique to detect and qualify substances in blood.

Why is  U1-nRNP Antibodies test suggested?

U1-nRNP Antibodies test is not a diagnostic test but it may be suggested to,

  • Evaluate a patient with symptoms of systemic disease.
  • Monitor patient’s condition for disease management.
  • Confirm the disease in case it has been detected by other tests.

How is U1-nRNP Antibodies test performed?

U1-nRNP Antibodies test is performed simply using fluorescent dyed ELISA kit strip.

  • Patient’s blood is taken for specimen.
  • Serum is added to polystyrene strip of ELISA.
  • Lasers are used to study results.

The value of U1-nRNP Antibodies test if >= 1.0 means a positive result.

What are the parameters measured in U1-nRNP Antibodies test?

The parameters studied in U1-nRNP Antibodies test are,

  • Presence of RNP antibodies.
  • Amount of RNP antibodies.

Preparation before performing  U1-nRNP Antibodies test

Any special preparations for U1-nRNP Antibodies test aren’t required. You may,

  • Inform your doctor about any ongoing medications.
  • Inform your doctor of or any health condition, for specific instructions before U1-nRNP Antibodies test .

Post-care after U1-nRNP Antibodies test

Any specific post-care is not required after U1-nRNP Antibodies test . You may,

  • Leave in its place the dressing strip for at least 30 minutes.
  • Take proper rest.
  • Avoid tight clothing on arm after U1-nRNP Antibodies test.

Sample types in U1-nRNP Antibodies test

The optimal sample volume for U1-nRNP Antibodies test is 0.5 ml.

  • Serum gel, refrigerated(preferred)
  • Serum, frozen

Side effects/risks of  U1-nRNP Antibodies test

U1-nRNP Antibodies test doesn’t show any distinct side effects. Those of a blood test can be taken into account.

  • Bruising
  • Swelling
  • Discomfort
  • Mood changes

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