Vitamin B12 is essential for growth, blood cells, for immune function and for good cardiovascular health and a deficiency of the same can cause an impairment in the functioning of the body. Transcobalamin is a protein that is required for the absorption and transport of Vitamin B12.
What is Transcobalamin?
Transcobalamin is a protein normally present in the blood, and good levels of it indicate adequate levels of Vitamin B12. It has 2 forms: Unbound Transcobalamin and HoloTranscobalamin (which is bound to Vitamin B12). A deficiency of Transcobalamin can be acquired or genetic, the former being much more common.
Why is Transcobalamin suggested?
Transcobalamin is suggested if you are showing the following symptoms:
- Fatigue, tiredness, weakness
- Recurrent infections
- Cuts and bruises that take a long time to heal.
How is Transcobalamin performed?
Transcobalamin testing requires:
- A blood sample that is taken from the vein of your arm
- The blood is then centrifuged and the serum that separates is taken for further testing
- Serum holotranscobalamin, Vitamin B12, and Homocysteine levels are useful for better diagnosis.
What are the parameters measured in Transcobalamin?
In Transcobalamin testing the normal values are:
- Transcobalamin: 670-1270 pmol/L
- HoloTranscobalamin: 42-157 pmol/L
- Vitamin B12: 200-900 ng/ml
- Homocysteine: 4-15 𝜇mol/L
Preparation before performing Transcobalamin
It is a simple blood test that requires no special preparation from the testee.
Post-care after Transcobalamin
No specific post care is required.
Sample types in Transcobalamin
The sample type involved during Transcobalamin testing is a blood sample from the patient’s body.
Side effects/ risks of Transcobalamin
There are no risks associated with Transcobalamin testing.