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Pseudo-Cholinestrase

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Overview

Detailed description of pseudocholinesterase enzyme and its effects in the body were demonstrated below.

What is pseudocholinesterase?

Pseudocholinesterase an enzyme presents in blood and certain organs which hydrolyses acetylcholine more slowly than acetylcholinesterase. Pseudocholinesterase is a glycoprotein, produced by liver, circulating in the plasma. It specifically hydrolyses exogenous choline esters. (2)

Why is pseudocholinesterase suggested?

Studies suggest that pseudocholinesterase may be involved in transmission of nerve signals. Lack of functional pseudocholinesterase impairs the body ability to break down the choline ester efficiently, leading to abnormal prolonged effects.

How pseudocholinesterase is measured in body?

Laboratory tests shows diagnosis of pseudocholinesterase deficiency is made by plasma assays of pseudocholinesterase enzyme activity. (1)

What are the parameters measured for pseudocholinesterase?

Cholinesterase activity is correlated with plasma triglycerides, serum glutamyltransferases, aspartate aminotransferase, alanine aminotransferase, urate, serum pseudocholinesterase levels. (3)

NANA

Samples of pseudocholinesterase:

Plasma cholinesterase (also known as pseudocholinesterase, butyryl cholinesterase, or BuChE). (6)

Side effects of pseudocholinesterase:

Some of the side effects associated with pseudocholinesterase includes: (4)

  • Anxious mood.
  • Fatigue
  • Pain
  • Stress
  • Depressed mood.

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