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Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G

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Overview brief

Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G is an essential regulatory component of the fibrinolytic pathway.

What is a Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test?

Elevated plasma levels of Plasminogen activator inhibitor-1 (PAI-1) increase the risk for type 2 diabetes. The Plasminogen Activator Inhibitor-1(PAI-1) 4G/5G test is a major genetic determinant of plasma PAI-1 levels, with 4G/4G homozygotes having elevated PAI-1 levels relative to 5G allele carriers.

Why is Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test suggested?

Plasminogen Activator Inhibitor (PAI-1) 4G/5G is suggested if the patient suffers from the following symptoms:

  • Prolonged nosebleeds
  • Easy bruising.

How is Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test performed?

Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test is performed as follows:

  • The blood sample is collected from the patient’s veins.
  • The sample is sent to the lab for analysis.

What are the parameters measured in Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test?

Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test measures the level of PAI-1 antigen and tPA antigen present in the patient’s blood.

Preparation before performing plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test.

No special preparation is required for the Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test. The preparation for the test includes:

  • Discuss medical history with the doctor.
  • Wear loose clothes.

Post-care after Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test.

No special post-care is needed after Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test simple steps to follow are:

  • The patient can go home after the blood is collected.

 

Sample types of Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test.

Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G requires only one sample:

  • Intravenous blood sample.

Side effects/risks of Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test.

Effects of Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G test can be severe as follow:

  • The patient might have several punctures if the vein cannot be easily located.
  • The patient might experience discomfort.

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