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Plasminogen Activator Inhibitor-1

Overview brief

Plasminogen Activator Inhibitor-1 test help to detect deficiency of Plasminogen Activator Inhibitor-1 in the patient’s body

What is a Plasminogen Activator Inhibitor-1 test

Plasminogen Activator Inhibitor-1(PAI-1) is a potent inhibitor of tissue plasminogen activator (tPA) and urokinase-type plasminogen activators, which are primarily responsible for the initiation of fibrinolysis. Plasminogen Activator Inhibitor-1 test help to detect deficiency of PAI-1.

Why is Plasminogen Activator Inhibitor-1 test suggested?

Plasminogen Activator Inhibitor-1 test is suggested if the patient suffers from the following symptoms:

  • Prolonged nosebleeds
  • Excessive bleeding after the medical or dental procedure.
  • Easy bruising.

How is Plasminogen Activator Inhibitor-1 test performed?

Plasminogen Activator Inhibitor-1 test is performed as follows:

  • The blood sample is collected from the patient’s veins.
  • The sample is sent to the lab for analysis.

What are the parameters measured in Plasminogen Activator Inhibitor-1 test?

Plasminogen Activator Inhibitor-1 test measures the level of PAI-1 antigen and tPA antigen present in the patient’s blood.

Preparation before performing plasminogen Activator Inhibitor-1 test.

No special preparation is required for the Plasminogen Activator Inhibitor-1 test. The preparation for the test includes:

  • Discuss medical history with the doctor.
  • Wear loose clothes.

Post-care after Plasminogen Activator Inhibitor-1 test.

No special post-care is needed after Plasminogen Activator Inhibitor-1 test simple steps to follow are:

  • Take rest for some time
  • The patient can go home after the blood is collected.

Sample types of Plasminogen Activator Inhibitor-1 test.

Plasminogen Activator Inhibitor-1 requires only one sample:

  • Intravenous blood sample.

Side effects/risks of Plasminogen Activator Inhibitor-1 test.

Effects of Plasminogen Activator Inhibitor-1 test can be severe as follow:

  • The patient might have several punctures if the vein cannot be easily located.
  • The patient might experience discomfort.

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