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PLAP (Placental Alkaline Phosphatase)

Overview

The PLAP (Placental Alkaline Phosphatase) test is a tumor marker to detect primary intracranial germinoma.

What is PLAP?

The PLAP (Placental Alkaline Phosphatase) is used to detect cancer. PLAP is produced by syncytiotrophoblasts after the twelfth week of pregnancy. PLAP can be found in both malignant somatic and germ cell tumors. PLAP (Placental Alkaline Phosphatase) can be useful in differentiating seminoma and embryonal carcinomas from undifferentiated malignant tumors.

Why is PLAP suggested?

Your doctor will ask you to get a PLAP (Placental Alkaline Phosphatase) test for

  • Low back pain.
  • Dyspnea
  • Cough
  • Haemoptysis
  • Neurologic abnormalities.

How is PLAP performed?

The PLAP (Placental Alkaline Phosphatase) test is done by collecting

  • A formalin-fixed, paraffin-embedded tissue block.
  • An unbaked, unstained slide for H&E staining and two to three positively charged unstained slides for each test or the antibody being tested for.

What are the parameters measured in PLAP?

The PLAP (Placental Alkaline Phosphatase) test measures the level of phosphate in the body. The test process differs from laboratory to laboratory.

Preparation before performing PLAP

There is no special preparation necessary for a PLAP (Placental Alkaline Phosphatase) test.

Post-care after PLAP

There is no post-care necessary after the PLAP (Placental Alkaline Phosphatase) test. You will be able to return to your regular life after the PLAP test.

Sample types in PLAP

The sample type in PLAP (Placental Alkaline Phosphatase) test is a tissue sample

Side effects/risks of PLAP

Certain medications that you may be taking can influence the results of PLAP (Placental Alkaline Phosphatase) test. You should inform your doctor about all the medicines you are taking to avoid an incorrect diagnosis.

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