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CK5/6

Overview Brief

 CK5/6 is a highly useful antibody in diagnostic Surgical Pathology.

What is CK5/6 Test?

Cytokeratin 5-6 is an antibody examined in laboratory for the recognition of cytokeratin 5 and 6 proteins in formalin-fixed paraffin-embedded (FFPE) human tissues by means of immunohistochemistry (IHC). [1]

Why is CK5/6 Test suggested?

In the CK5/6 Test the Cytokeratin 5-6 antibody labels mesothelioma, along with epithelial basal cells in prostate and tonsil, and differentiate the malignant mesothelioma from pulmonary adenocarcinoma. It does not act in response with other mesodermally derived tissues, like muscle and connective tissues. Furthermore, Anti-CK 5-6 has been found valuable in the differential diagnosis of uncommon proliferations of the breast. [1]

How is CK5/6 Test performed?

Typically, a blood sample is drawn from a vein in the arm in the CK5/6 Test.

What are the parameters measured in the CK5/6 Test?

The normal value in CK5/6 Test for all ages and genders is >100kU/l. [1]

Preparation before performing CK5/6 Test

It is advisable to ask the physician about any particular instruction to be followed prior to appearing for a blood test. If you are presently on any medication or consuming other supplements you may need to take a break from it in certain cases. [1]

Post-care after CK5/6 Test

CK5/6 Test is a simple procedure. No special care is required post the sample for testing has been given.  A bandage may be required as blood is drawn.

Sample types in CK5/6 Test

Blood sample is taken in CK5/6 Test.

Side effects/risks of CK5/6 Test

There are no risks associated with CK5/6 Test .

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