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Beta 2 Microglobulin Serum

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Overview Brief

If you have been diagnosed with certain cancers like multiple myeloma, a Beta 2 Microglobulin Serum test is your best bet for monitoring the progress of the disease.

What is Beta 2 Microglobulin Serum?

Beta 2 Microglobulin Serum test is a blood serum test conducted to measure the levels of the Beta 2 Microglobulin protein in the body.

Beta 2 Microglobulin (B2M) is a type of cell membrane protein whose levels in the bloodstream and the urine increase significantly during the body’s immune response to certain diseases. The Beta 2 Microglobulin Serum test, therefore, works as a tumor marker for certain malignancies like multiple myeloma.

A higher level of B2M protein as indicated by the Beta 2 Microglobulin Serum test may indicate aggressive or non-responding disease.

Why is Beta 2 Microglobulin Serum suggested?

The Beta 2 Microglobulin Serum test is typically suggested for the following reasons.

  • To monitor the progress of diseases like multiple myeloma and certain lymphomas [1].
  • To assess the prognosis of such diseases.

How is Beta 2 Microglobulin Serum performed?

Beta 2 Microglobulin Serum is performed by a trained pathologist.

  • A blood sample is collected from a vein in the arm.
  • The sample is centrifuged to separate the serum.
  • The serum can be stored in a refrigerator for up to five days at 2-8 degrees Celsius [2].

To complement the Beta 2 Microglobulin Serum, a urine sample may also be taken.

What are the parameters measured in Beta 2 Microglobulin Serum?

The following parameters are measured in Beta 2 Microglobulin Serum

  • Level of B2M protein range in blood serum.

Preparations before performing Beta 2 Microglobulin Serum

The following preparations are recommended before Beta 2 Microglobulin Serum

  • Overnight fasting.
  • Informing physician of all medicines including herbal supplements.

Post-care after Beta 2 Microglobulin Serum

No specific post-care is required for Beta 2 Microglobulin Serum.

Sample types with Beta 2 Microglobulin Serum

The following sample types are needed for Beta 2 Microglobulin Serum.

  • Serum sample.
  • Urine sample.
  • Cerebrospinal fluid sample.

Side effects/risks of Beta 2 Microglobulin Serum

Beta 2 Microglobulin Serum has the following potential risks

  • Distorted results due to certain drugs or radiographic contrast chemicals.

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