Oligoclonal Bands

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Overview Brief

Oligoclonal Bands is a test taken to look for inflammation-related proteins in the cerebrospinal fluid (CSF).

What is Oligoclonal Bands?

Oligoclonal Bands is a test done on the CFS (Cerebrospinal Fluid).

The Oligoclonal Bands test finds out the reason that is causing inflammation of the Central Nervous System (CNS) caused by a protein called an Immunoglobulin, and if not present in your blood, you may have Multiple Sclerosis (MS).

Why is Oligoclonal Bands suggested?

Oligoclonal Bands tests are suggested to diagnose MS, as Immunoglobulins play an essential role in the body’s immune system.

How is Oligoclonal Bands performed?

For an Oligoclonal Bands test, the patient needs to put on a back open hospital gown.

  • The patient will need to lie down sideways to expose the back.
  • A local anesthetic is given.
  • Then a hollow needle is inserted into the lower spine, and a small quantity of CSF is collected and sent to a laboratory for analysis.

 What are the parameters measured in Oligoclonal Bands?

Oligoclonal bands are measured in milligrams per liter.

Preparation before performing Oligoclonal Bands

No Specific preparation is required before an Oligoclonal Bands test, but you need to inform the doctor if you have back or spine problems or if you are taking any medication which is related to the spine or blood.

Post-care after Oligoclonal Bands

After an Oligoclonal Bands test, the patient should lie flat to reduce the risk of headaches and later can return back to normal daily activities. Talk with your doctor, and they will help you best in further procedures after your reports.

Sample types in Oligoclonal Bands

During an Oligoclonal Bands test a serum sample is taken at the time of the lumbar puncture.

Side effects/risks of Oligoclonal Bands

After an Oligoclonal Bands test, there can be

  • Headache and back pain, which usually starts a day or two after the Oligoclonal Bands
  • There is a risk of bleeding where the needle was inserted.

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