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JAK-2 Mutation

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Overview

JAK-2 Mutation occurs due to the improper functioning of the gene JAK-2, which ultimately results in bone marrow diseases.

What is the JAK-2 Mutation test?

JAK-2 Mutation is a condition in which the JAK-2 gene guides the cells to produce the JAK-2 protein. The JAK-2 protein

  • Facilitates cell growth and division.
  • Controls the blood cell production in the bone marrow.

The JAK-2 gene is finally responsible for subsequent disorders of the bone marrow.

Why is the JAK-2 Mutation test suggested?

JAK-2 Mutation is suggested in the following cases:

  • If the medical practitioner suspects the presence of a bone marrow disorder such as polycythemia vera, thrombocythemia, or primary myelofibrosis.
  • If myeloproliferative neoplasms are also detected in the test for JAK-2.

How is the JAK-2 Mutation test performed?

JAK-2 Mutation is performed in the following steps:

  • The patient’s blood sample is collected either from his bone marrow or from the vein.
  • The sample is sent to the lab for the detection of the gene JAK2.

What are the parameters measured in JAK-2 Mutation?

The parameters measured in JAK-2 Mutation include the Janus Kinase 2 gene.

Preparation before performing JAK-2 Mutation

There are no specific preparations for JAK-2 Mutation.

Post-care after JAK-2 Mutation

Post-care for JAK-2 Mutation is:

  • The patient can follow-up with the doctor to weigh the treatment options.

Sample types in JAK-2 Mutation

A sample of JAK-2 Mutation is drawn from the bone marrow or the vein of the patient.

Side effects/risks of JAK-2 Mutation

Side effects of JAK-2 Mutation include the possibility of temporary soreness and bruising due to the needle prick.

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