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Intrinsic Factor IgG Antibody

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Overview

The Intrinsic factor IgG Antibody is a protein in the body that is associated with pernicious anemia.

What is the Intrinsic Factor IgG Antibody?

The Intrinsic Factor IgG Antibody is produced by specialized cells in the stomach walls, which are called parietal cells.

  • Intrinsic Factor IgG Antibody deficiency leads to vitamin B12 deficiency.
  • The test helps detect the amount of Intrinsic Factor IgG Antibody circulating in the blood. The Intrinsic Factor IgG Antibody test is often used with a test to detect parietal cell antibodies to confirm the diagnosis of pernicious anemia.

Why is an Intrinsic Factor IgG Antibody test suggested?

The Intrinsic Factor IgG Antibody test is an uncommon test, which is suggested when

  • The doctor suspects pernicious anemia or severe Vitamin B12 deficiency.
  • The patient notices symptoms like weakness, fatigue, paleness, tingling, or numbness.

How is an Intrinsic Factor IgG Antibody test performed?

To perform an Intrinsic Factor IgG Antibody test,

  • The healthcare professional will draw blood from a vein in the patient’s forearm.
  • The area of the needle prick is cleaned with antiseptic.
  • A tourniquet is tied above the area of the intended prick.

The Intrinsic Factor IgG Antibody test is performed routinely, unlike many other routine tests.

What are the parameters measured in an Intrinsic Factor IgG Antibody test?

During an Intrinsic Factor IgG Antibody test,

  • Decreased vitamin B12 levels along with increased methylmalonic acid and homocysteine levels indicate pernicious anemia.
  • Normal vitamin B12 levels do not mean that you do not suffer from pernicious anemia. You may be asked to perform further tests.

Preparation before performing an Intrinsic Factor IgG Antibody test

There is no special preparation needed before an Intrinsic Factor IgG Antibody test.

Post-care after an Intrinsic Factor IgG Antibody test

There are no post-care measures after an Intrinsic Factor IgG Antibody test.

Sample types in an Intrinsic Factor IgG Antibody test

For testing an Intrinsic Factor IgG Antibody, a blood sample should be considered to extract serum for testing.

Side effects/risks of an Intrinsic Factor IgG Antibody test

There are side effects/risks involved in an Intrinsic Factor IgG Antibody test.

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