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DOG-1 is found to be a very significantly specific marker that is used for the diagnosis of gastrointestinal stromal tumor (GIST).

What is DOG-1?

DOG-1 is a protein found on the surface of the cell that is known to have functions in gastrointestinal stromal tumors. With a DOG-1 test, the doctors diagnose for GIST and start treating the disease.

Why is DOG-1 suggested?

DOG-1 is suggested to the patient when he/she experiences the following symptoms

  • Nausea
  • Bloody stools.
  • Discomfort
  • Fatigue
  • Difficulty in swallowing.

How is DOG-1 performed?

The procedure in which the DOG-1 test is performed involves the following steps:

  • The patient will be asked to visit an outpatient clinic laboratory.
  • In the clinic, the patient will have to sit still while the examiner will extract tissue cells from a part of the patient’s body.
  • The tissue cells will be stored in paraffin-embedded cases and taken to the laboratory.

The DOG-1 test checks for gastrointestinal stromal tumors in the samples and sends the results to the patient.

What are the parameters measured in DOG-1?

With the help of the DOG-1 test, the doctors measure the majority of cKIT negative and other factors that trigger the GIST in the patients.

Preparation before performing DOG-1

You should inform your doctor about your medical history, any current medications you are on, and family conditions.

Post-care after DOG-1

Post-care after DOG-1 includes:

  • Take proper rest.
  • Take the medications prescribed, regularly.

Sample types in DOG-1

The sample types in DOG-1 are as follows:

  • Paraffin-embedded tissue samples.
  • Blood samples.

Side effects of DOG-1

Common side effects of DOG-1 are

  • Nausea if sedated before taking tissue samples.
  • Discomfort
  • Slight pain.

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