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Desmoglein III Antibody

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Overview Brief

Pemphigus is the description of fatal autoimmune, blistering diseases characterised by intraepithelial lesions. It is a severe kind of skin disease. In the case of patients having pemphigus, Antibodies to Desmoglein 3 (DSG3) are present.

What is DESMOGLEIN III ANTIBODY?

Pemphigus foliaceus, present in basal lower layers of skin, will produce antibodies to DSG3. Pathogenicity of Desmoglein-3 antibodies derives from the existence of a tryptophan residue that interacts with the binding pocket which is necessary for trans-interaction of Desmoglein molecules. Such antibodies can lead to the cause of skin disorders like pemphigus vulgaris.

Why is DESMOGLEIN III ANTIBODY suggested

DESMOGLEIN III ANTIBODY symptoms can vary depending on the levels. Symptoms are as below:

  • Pemphigus.

How is DESMOGLEIN III ANTIBODY performed?

DESMOGLEIN III ANTIBODY tests may include:

  • About 3ml or just two teaspoons of the blood sample will be drawn from your body.
  • This test needs to be conducted in a well-equipped diagnostic lab with Desmoglein-Antibodies-3 test facility.
  • The skin is cleaned with an alcohol pad.
  • The needle is inserted into the body through the vein.
  • The blood sample will be collected to the needle which contains the serum gel.

What are the parameters measured in DESMOGLEIN III ANTIBODY?

DESMOGLEIN III ANTIBODY test can be conducted via the following methods:

  • Desmoglein III Antibody test is done via a blood test or tissue sample test.

 

Preparation before performing DESMOGLEIN III ANTIBODY

The preparation for the DESMOGLEIN III ANTIBODY test includes:

  • Discuss medical history and allergies with the doctor.
  • Do not wear full sleeves, jacket or sweater.
  • Fasting overnight.

Post-care after DESMOGLEIN III ANTIBODY

You should take care of below steps for DESMOGLEIN III ANTIBODY:

  • Take proper rest.

Sample types in DESMOGLEIN III ANTIBODY

Few samples are for DESMOGLEIN III ANTIBODY as follows:

  • Blood test.

Side effects/risks of DESMOGLEIN III ANTIBODY

DESMOGLEIN III ANTIBODY blood test side effects are:

  • You may feel a small skin prick uneasy and have a little bruising where the needle goes in.

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