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Complement 3

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Overview Brief

Complement 3 Test is a blood test that measures the activity of a specific protein in the body.[1]

What is Complement 3 Test?

A Complement 3 Test might be used to examine patient with an autoimmune disorder. It is done to see if treatment for their condition is working. C3 and C4 are the most frequently measured complement components. Complement activity fluctuates throughout the body. [1]

Why is the Complement 3 Test suggested?

The Complement 3 Test may be conducted for the following conditions: [1]

  • Fungal infections.
  • Gram-negative septicemia.
  • Parasitic infections, such as malaria.
  • Paroxysmal nocturnal hemoglobinuria (PNH).
  • Shock.

How is Complement 3 Test performed?

Blood is drawn from a vein in the Complement 3 Test. Usually, a vein from the inside of the elbow or the back of the hand is preferred. [1]

What are the parameters measured in the Complement 3 Test?

The normal range in Complement 3 Test is 88 to 201 milligrams per deciliter (mg/dL) (0.88 to 2.01 g/L). Increased complement activity might indicate Cancer and Ulcerative colitis.

Decreased complement activity might be seen in Bacterial infections, Cirrhosis, Glomerulonephritis, Hepatitis, Hereditary angioedema, Kidney transplant rejection, Lupus nephritis, Malnutrition, Systemic lupus erythematosus, and Rare inherited complement deficiencies. [1]

Preparation before performing Complement 3 Test

There is no special preparation needed before Complement 3 Test.

Post-care after Complement 3 Test

Complement 3 Test is a simple procedure. No special care is required post the sample for testing has been given.  A bandage may be required as blood is drawn.

 Sample types in Complement 3 Test

A blood sample is taken in the Complement 3 Test.

Side effects/risks of Complement 3 Test

There are no risks associated with having blood drawn in the Complement 3 Test. The patient might feel lightheaded in the worst case scenario.

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