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Cholinesterase

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Overview

A Cholinesterase test is performed to diagnose symptoms of pesticide poisoning. People using pesticides and insecticides as part of their work should get the test done regularly, to monitor the toxicity.

What is Cholinesterase Test?

The Cholinesterase test is a blood test to measure the activity levels of Cholinesterase enzymes in the body. The Cholinesterase test is performed to diagnose an inherited pseudocholinesterase deficiency and to detect organophosphate pesticide exposure, which inhibits Cholinesterase activity.

Why is the Cholinesterase test Suggested?

The Cholinesterase test is suggested to assess serious exposure to organophosphate compounds. Some symptoms include

  • Dizziness and headache.
  • Excessive tearing, sweating, or salivation.
  • Vomiting, nausea.
  • Muscle weakness and twitching.
  • Breathing difficulties.

How is the Cholinesterase Test Performed?

The Cholinesterase Test is performed at registered pathology labs. The procedure includes the following steps:

  • Intravenous blood sample is collected.
  • The sample is tested to determine Cholinesterase activity.

The decreased activity level of Cholinesterase enzymes in the Cholinesterase test indicates high absorption of organophosphate compounds.

What are the Parameters Measured in the Cholinesterase Test?

The Cholinesterase test measures the activity levels of Cholinesterase enzymes.

Preparation before Cholinesterase Test

Here are some preparative measures to consider before a Cholinesterase test:

  • The patient should discuss medical history and medication with the doctor.
  • The doctor’s prohibitions should be followed.
  • The instructions of the lab technician should be followed during the test.

Post-care after Cholinesterase Test

Providing a sample for the Cholinesterase test takes around 10 minutes. Except for a slight prick when the sample is collected, there is no pain or discomfort.

  • Rest for some time if you feel lightheaded or dizzy after submitting the sample for the Cholinesterase test.
  • Report excessive bleeding or pain at the site of sample collection to the doctor, if applicable.

Sample Types in Cholinesterase Test

Cholinesterase Test is performed using an intravenous blood sample.

Side-effects of Cholinesterase test

The patient has to submit a blood sample at a laboratory for the Cholinesterase test. Side effects include

  • Risk of excessive bleeding from the sample collection spot.
  • Weakness or lightheadedness after submitting a sample for the Cholinesterase test.

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