Centromere AntiBody IgG (IFA)

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Centromere Antibodies IgG(IFA) occur primarily in patients with the Calcinosis, Raynaud Phenomenon, Esophageal Dysfunction, Sclerodactyly, and Telangiectasia syndrome variant of systemic sclerosis.

What is Centromere Antibody IgG(IFA)?

Centromere Antibody IgG(Immunoglobulin G) IFA(Indirect Fluorescent Antibody) is a test to check the presence of centromere antibodies associated with CREST syndrome, a variant of systemic sclerosis which targets centromere B an antigen of the centromeric complex.

Why is Centromere Antibody IgG(IFA) suggested?

Centromere Antibody IgG(IFA) is suggested if a person is suspected that Immunoglobulin G targets centromere B a dominant antigen. The symptoms of Centromere Antibody IgG(IFA) are

  • Autoimmune diseases including lupus, scleroderma
  • Mixed connective tissue disease
  • Autoimmune hepatitis
  • Rheumatoid arthritis(RA)

How is Centromere Antibody IgG(IFA) performed?

Centromere Antibody IgG(IFA) test is performed by:

  • Blood exams can be tested for antibodies that are frequently found in the blood of people.
  • Skin tests are conducted under a microscope.
  • Tests to identify lung, heart, gastrointestinal can also be conducted.

What parameters are measured in Centromere Antibody IgG(IFA)?

Centromere Antibody IgG(IFA) test measures:

  • If Immunoglobulin G is reacting to centromere B.
  • Measuring of systemic scleroderma.

Preparation before Centromere Antibody IgG(IFA)

No prior preparation is needed before performing the test, but you may need to

  • Not to take anything before the test.
  • He will ask to take glucose or juice.

Post-care after Centromere Antibody IgG(IFA)

There is no post care requirement after the test, but one with positive results must

  • Taking regular medicines provided by the doctor.
  • Avoiding various food and products as said by the doctor.
  • If a person is feeling uncomfortable he should take some rest.

Sample types in Centromere Antibody IgG(IFA)

Only a few samples are required

  • Blood sample
  • Skin biopsy

Side effects/risks of Centromere Antibody IgG(IFA)

There are no side effects of this test, however, the following problems may arise:

  • Taking blood samples can be painful.
  • Skin piercing can also be painful.

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