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The BER-EP4 test is used to investigate the presence of basal cell carcinomas which are the most common in the world with almost 105 rises reported each year.

What is BER-EP4?

BER-EP4 or the Epithelial cell adhesion molecule is done to evaluate the basal cell carcinomas.

  • BER-EP4 is a test which can distinguish and classify the different categories of the carcinomas.
  • Infiltrative basal cell carcinoma is considered as the most difficult to treat among the 3 types.
  • Using this test, basal cell carcinomas can be distinguished from squamous cell carcinoma.
  • Similarly, mesothelioma can be differentiated from pulmonary adenocarcinoma.

Surgeries are an option of treatment for the BER-EP4.

Why is BER-EP4 suggested?

BER-EP4 is suggested for the following symptoms:

  • Redness of skin.
  • Shiny pearl-like nodules over the skin.
  • Red patchy skin similar to eczema.
  • Skin Thickening.

How is BER-EP4 performed?

BER-EP4 is performed as follows:

  • The tissue sample and a needle aspirate sample is collected in RPMI medium.
  • The tissue sample is sieved and made into a suspension.
  • The suspension is filtered and washed and sent for testing.

The BER-EP4 test thrives only on healthy tissues and cannot be done depleted samples.

What are the parameters measured in BER-EP4?

Parameters measured in BER-EP4 are:

  • The tissues collected are tested to distinguish them from the carcinoma cells.

Preparation before performing BER-EP4

  • No specific preparation is required for BER-EP4.


Post-care after BER-EP4

Post-care for BER-EP4 is:

  • Treatment options can be discussed based on the results of the test.

Sample types in BER-EP4

Sample types in BER-EP4:

  • Tissue samples
  • Needle aspirate sample

Side effects/risks of BER-EP4

There may be the following side effects:

  • Bruising from sample collection.
  • Soreness at the site of sample collection.

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