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Bcr-Abl Gene Translocation (Quantitative)

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The Bcr-Abl Gene Translocation (Quantitative) test is used to investigate the presence of the oncogene or the Philadelphia chromosome.

What is Bcr-Abl Gene Translocation (Quantitative)?

Bcr-Abl Gene Translocation (Quantitative) is a test which detects the presence of the abnormal fusion gene sequence in people suffering from leukemia.

  • The test is done for a person with an abnormal or unusual presence of WBCs in the bone marrow and has the Philadelphia chromosome.
  • A person may not show any symptoms while suffering from the disorder.
  • There are various methods to confirm the sequence, such as the molecular testing or cytogenetics or fluorescence in situ hybridization.

Bcr-Abl Gene Translocation (Quantitative) confirms if the person is Ph-positive ALL.

Why is Bcr-Abl Gene Translocation (Quantitative) suggested?

Bcr-Abl Gene Translocation (Quantitative) is suggested for the following symptoms:

  • Weight loss.
  • Enlarged spleen.
  • Severe pain in bones or joints.

The test is suggested when the doctor suspects an unusual pattern of the chromosome.

How is Bcr-Abl Gene Translocation (Quantitative) performed?

Bcr-Abl Gene Translocation (Quantitative) is performed as follows:

  • The blood sample is collected from the arm of the patient.
  • The tissue sample is sieved and made into a suspension.
  • The sample is tested in the lab under the microscope for the unusual pattern of the chromosome.

If BCR-ABL1 is found, it confirms the diagnosis of CML or one of the types of ALL.

What are the parameters measured in Bcr-Abl Gene Translocation (Quantitative)?

Parameters measured in Bcr-Abl Gene Translocation (Quantitative) are:

  • Abnormal chromosome 22 or abnormal gene fusion to check some types of leukemia.

Preparation before performing Bcr-Abl Gene Translocation (Quantitative)

  • No specific preparation is required for Bcr-Abl Gene Translocation (Quantitative).

Post-care after Bcr-Abl Gene Translocation (Quantitative)

Post-care for Bcr-Abl Gene Translocation (Quantitative) is:

  • Confirming the treatment options or surgeries based on the results of the test.

Sample types in Bcr-Abl Gene Translocation (Quantitative)

Sample types in Bcr-Abl Gene Translocation (Quantitative):

  • A blood sample from the vein or the bone marrow.

Side effects/risks of Bcr-Abl Gene Translocation (Quantitative)

There may be the following side effects:

  • Bruising due to sample collection.
  • Soreness because of the prick.

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