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Apolipoprotein – A1

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The Apolipoprotein – A1 Test is a quantitative test to help identify if there is an adequate amount of Apolipoprotein – A1, which determines the risk of cardiovascular disease.

 

What is Apolipoprotein – A1 Test

Apolipoproteins are the major components of HDL- High-Density Lipoprotein. Lipids are not soluble by themselves in blood and apolipoproteins help dissolve the lipids and transport them through the bloodstream. Deficiencies in Apo A-1 leads to cardiovascular diseases.  The decrease in Apo- A1 may also be due to chronic kidney disease, obesity, uncontrolled diabetes etc.

Why is Apolipoprotein – A1 Test suggested?

The Apolipoprotein – A1 Test is suggested in the following cases:

  • A low value of HDL-C.
  • High cholesterol and triglycerides.
  • During assessment for Cardiovascular Disease.
  • In cases of family history of cardiovascular disease.

How is an Apolipoprotein – A1 Test performed?

The Apolipoprotein – A1 Test is a short procedure.

  • A vein is located, often inner arm and the area is cleaned.
  • A needle is used to draw blood from the vein.
  • An adhesive is placed after the sample is drawn.
  • The sample is sent to the laboratory for testing.

What are the parameters measured in the Apolipoprotein – A1 Test?

The Apolipoprotein – A1 Test tests for an adequate quantity of  Apolipoprotein -A1, as it the major component of HDL – High-Density Lipoprotein which determine the amount of cholesterol in the body.

Preparation before performing Apolipoprotein – A1 Test

The Apolipoprotein – A1 Test does not require any fasting, but it is usually performed alongside a lipid profile which requires 12 hours of fasting.

Post-care after Apolipoprotein – A1 Test

The Apolipoprotein – A1 Test does not have any side effects that require treatment or attention.

Sample types in Apolipoprotein – A1 Test

The reference range of Apo-A1 varies by sex and is as follows:

Men

  • Greater than 120 mg/dL (1.2 g/L): Negative.
  • Lesser than 120 mg/dL (1.2 g/L): Likely to have cardiovascular disease

Women

  • Greater than 140 mg/dL (1.4 g/L): Negative.
  • Lesser than 140 mg/dL (1.4 g/L): Likely to have cardiovascular disease.

Side Effects of Apolipoprotein – A1 Test

The drawing of blood might make a few people feel dizzy.

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