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Anti Centromere Antibodies

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Overview Brief

Anti Centromere Antibodies is a test to detect the presence of anti-centromere antibodies, which occur in some autoimmune diseases.

What is an Anti Centromere Antibodies Test?

Anti Centromere Antibodies (also known as centromere antibody ACA) test measures the level of ACA, a protein that is produced by the immune system. This blood test aids in the diagnosis of limited cutaneous scleroderma, which is a rare connective tissue disorder.

Why is Anti Centromere Antibodies Suggested?

Anti Centromere Antibodies is suggested by a doctor to diagnose symptoms of the CREST syndrome:

  • Calcium deposits under the skin.
  • Decreased blood flow to toes and fingers, which makes them turn blue or white.
  • Esophageal dysfunction.
  • Thick and shiny skin on hands and fingers.
  • Red spots on the skin.

How is Anti Centromere Antibodies Performed?

Anti Centromere Antibodies is a blood test performed at a lab.

  • An intravenous blood sample is collected.
  • The sample is tested for the presence of ACA antibodies using indirect immunofluorescence.

The results of Anti Centromere Antibodies are given in positive and negative. Positive results indicate the person has limited cutaneous scleroderma.

What are the Parameters Measured in Anti Centromere Antibodies?

Anti Centromere Antibodies measures the presence of ACA in the sample.

Preparation before Performing Anti Centromere Antibodies

No specific preparation is required before Anti Centromere Antibodies.

  • You will be informed if fasting is required.
  • Pre-schedule the test.

Post-care after Anti Centromere Antibodies

Only people suffering from symptoms of CREST syndrome are suggested to take the Anti Centromere Antibodies test.

  • Rest for some time before you resume routine.
  • Follow instructions of the lab technician.

Sample Types in Anti Centromere Antibodies

Anti Centromere Antibodies is performed using a single intravenous blood sample.

Side-effects/risks of Anti Centromere Antibodies

Anti Centromere Antibodies is a safe test.

  • Slight prick when the sample is collected from veins to test for Anti Centromere Antibodies.
  • Pain at the sample site.

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