Albumin/Globulin Ratio

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Albumin/Globulin Ratio

Albumin and globulin are two major proteins seen in the human serum. The albumin to globulin (A/G) ratio is used as an index of disease state

What is A/g ratio?

The A/G ratio is the amount of albumin in the serum divided by the globulins. The ratio is put to use in order to identify the causes of change in total serum protein. The normal ratio is .08-2.0 It is a calculated value and may go out of the normal range if one component increases or decreases relative to the other.

Why is A/g ratio suggested?

The test is suggested in case there is:-

  • Lack of appetite.
  • Nausea and vomiting.
  • Puffiness around eyes and swelling of arms and legs(Nephrotic syndrome).
  • Yellowing of skin and eyes.

Thus, a regular check-up of the ratio is advised as it helps to diagnose liver and kidney disorders if any.

How is A/g ratio test performed?

The test requires a sample of blood which will be taken by the lab technician from a vein in your arm or by fingerstick. The blood then goes for testing and the results are back in about 12 hours.


No test preparation is needed.

Post care after A/G ratio test

If the results are abnormal then further testing is required to diagnose the disease affecting the protein levels in the blood, and medication needs to be taken accordingly.


Sample types in A/G ratio

Generally, two types of samples are possible-

  • Low protein level, indicating a liver or kidney problem.
  • High protein level, indicating a gastrointestinal problem.

No specific side effects.

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