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All You Need to Know about Ankylosis Spondylitis


A chronic condition that limits movement in the spine or other body parts

80 percent of children who inherit HLA-B27 from a parent with ankylosing spondylitis do not develop the disorder.[1]

- Treatable by a medical professional
- Requires a medical diagnosis
- Lab tests or imaging always required
- Chronic: can last for years or be lifelong

Ankylosing spondylitis (AS) is a type of arthritis of the spine. It causes inflammation between the vertebrae (bones structure that makes up your spine) and also affects the joints between your spine and pelvis. Most people also develop a protein alongside, a gene called HLA-B27, but it is not necessary that it causes AS. It is more likely to affect men as compared to women, and it is not a purely genetic disease.

Ages affected: Ages between 19 and 60: most often; From 6 to 18: often


Symptoms may include reduced flexibility of the spine or affected area.

People may experience
Pain areas: Back areas, ankles, knees, hip joints, neck, or shoulder
Eyes: Blurred vision, sensitivity to light, or redness
Inflammation areas: Spine, bowels, eyes, bone tissue, or tendons
Also common: Fatigue, hunched back, physical deformity, or sleep disorder


Self-care: Physical exercise can help increase the movement of the back, unless there are serious injuries present as well.

Medication: Steroids or nonsteroidal anti-inflammatory drugs may be prescribed as per the severity of the condition.

Specialists: For medical help, consult an orthopedic surgeon, a rheumatologist, or a physiotherapist. At mfine, you can choose from a range of doctors for a wide array of health issues.

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