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Atresia of foramina of Magendie and Luschka: A Rare Disorder


Atresia of foramina of Magendie and Luschka, also known as Dandy-Walker Malformation (DWM), is a rare congenital disorder of the brain which affects the cerebellum and the fluid-filled areas surrounding it.

Dandy-Walker malformation is estimated to affect 1 in 10,000 to 30,000 newborns. [1]

-Requires a medical diagnosis
-Requires a lab test or imaging
-Maybe chronic and can be lifelong
-No cure available, but can be managed

It may also lead to an enlarged fourth ventricle, cyst formation in the fourth ventricle, partial or complete absence of cerebellar vermis or increase in the size and pressure of hydrocephalus. The primary cause of DWM is chromosomal abnormalities.


During early infancy, the following symptoms are observed:
- Slow motor development
- Abnormal increase in the size of the skull
- Difficulty in breathing
- Presence of visible flat and widened veins in the skull

With the growing age, the following symptoms can be seen:
- Developmental delays
- Convulsions
- Mental retardation
- Vomiting
- Abnormal functioning of the pituitary gland, muscle, and eyes
- Delayed puberty
Visible symptoms include
- Very large circumference of the skull
- Swelling at back portion of the skull
- Malformation of the heart, face, limbs, fingers, and toes


Medication: Currently there is no cure available. However, the symptoms of DWM can be managed using:
- Surgical intervention, also known as a shunt, is carried out to drain out excess fluid accumulation and reduce intracranial pressure.
- Anticonvulsant medicines are prescribed to control seizures.

Specialists: Atresia of foramina of Magendie and Luschka is a serious congenital disorder which causes multiple health complications. Medical care must be sought at every stage to control the disorder from worsening. Feel free to contact our doctors at mfine for professional advice on all your health issues.

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