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Myopathy: Things to know about it

About


Myopathy is defined as the disease of muscles characterized by muscle weakness due to muscle fibre dysfunction.


Duchennes muscular dystrophy occurs in 1 in every 3,000 male births and has a prevalence of 3 per 100,000 [1]



- Indicates a long-term disease
- Presents a high risk of inflammatory myopathy in women
- Affects individual of all ages
- Shows that myopathy which is present from birth have life-threatening complications


Myopathy is classified into Acquired and Hereditary myopathies. Acquired myopathy includes endocrine, drug-induced, inflammatory, and toxic myopathies. Hereditary myopathy includes channelopathies; congenital myopathy; metabolic, mitochondrial, muscular dystrophies; and myotonias. Causes are genetics, systemic illness, certain drugs and medication, infections (rare), injury, etc. Diagnosis includes an evaluation of the patient's personal and family history, physical and neurological examinations, muscle biopsy, electromyography (EMG), exercise test, and genetic test.


Symptoms:


The symptoms mainly include muscular weakness, cramps, and sprains.


People may experience
Fatigue
Myalgia
Muscle atrophy
Contractures
Exercise intolerance
Stiffness


Treatment


Self-Care: Healthy and nutritious diet, changes in lifestyle, protection from the sun in case of dermatomyositis rash.


Clinical Treatment - Treatment depends on the condition and cause. It can include drug therapy, such as immunosuppressive, bracing to support weakened muscles, physical therapy, occupational therapy, medication, and surgery.


Medications: Corticosteroids, immunosuppressant agents, antibodies, and Intravenous immunoglobulin (IVIG) are proven to be effective.


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