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All you should know: Metabolic Encephalopathy


Metabolic encephalopathy (ME) is a disorder where abnormalities of brain function are caused by processes of extracerebral origin because of the chemical imbalance in the blood.

ME is most frequent in elderly people who have suffered from chronic illnesses, prolonged stay in bed previously. It is more common in people aged above 70 years.(1)
- Temporary or permanent
- Secondary to an underlying condition
- Can be acute or chronic
- Elderly people at risk
- Mild or extreme
- Treatment options available
- Laboratory tests, scans, and imaging are always required
ME is associated with diffuse cerebral dysfunction. It is not caused by a head injury. The treatment depends on the etiology, type, and severity of clinical presentation. It is characterized by various psychiatric, neurological symptoms and signs. It is evident in a range from very mild mental disorders to deep death and coma. It is manifested by epileptic seizures.


1. Kidney or liver failure
2. Blood infections
3. Hypoxia
4. Ischemia
5. Toxic agents
6. Systemic diseases
7. Low blood sugar, vitamin B1


People may experience the following symptoms:
1. Difficulty with memory, focusing, and problem-solving skills
2. Changing personality
3. Lethargy
4. Drowsiness
5. Involuntary twitching
6. Muscle weakness
7. Trembling
8. Seizures
9. Difficulty in speaking and swallowing
10. Coma
11. Severe confusion and disorientation


Its treatment depends on the cause and the type.
Self care: A healthy diet, nutritional supplements, smoking, and alcohol consumption cessation are recommended.

Medications: Antiepileptic medications and vitamin B1 supplements are helpful to treat symptoms or treat the underlying cause.

Specialists: Consult a neurologist for other concerns. In extreme cases, surgery may be required. At mfine, we provide a comprehensive treatment plan for optimum health.

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