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CREST Syndrome- Know all about it


CREST Syndrome is the less severe form of Scleroderma. It is also known as Limited Scleroderma causing tightening and hardening of the skin and connective tissues.

1 out of every 12,500 adults is affected by CREST Syndrome. Women are at a higher risk of developing this syndrome. F/M sex ratio is 4:1 in this case. [1]

CREST Syndrome is:

- Treatable but condition cannot be cured
- Requires a medical diagnosis
- Lab tests or imaging required
- Can last for years or lifelong

The disease is usually seen around the age between 40 to 50 years. The exact cause of this syndrome is not known. It originated from an autoimmune reaction leading to overproduction of collagen.


The common symptoms of CREST Syndrome include:
- C: Calcinosis, calcium deposits in the connective tissues
- R: Raynaud’s Phenomenon, Hands and feet turn white and then blue because of cold or anxiety
- E: Esophageal Dysfunction, difficulty in swallowing
- S: Sclerodactyly, thick and tight skin of fingers
- T: Telangiectasia, small red spots on hands and face


Self-care: Not much can be done to prevent or cure this disorder. However, people can keep their skin hydrated or moisturized with creams. Also, physical therapy helps in maintaining good muscle strength.

Medication: Treatment is usually focused on relieving the symptoms and preventing complications. Doctors may prescribe non-steroidal, anti-inflammatory medications and corticosteroids to relieve the pain. Immunosuppressive medications are also given to control the symptoms.

Specialists: In such cases, it is better to consult a Rheumatologist, Dermatologist, Immunologist, etc. for medical advice. mfine can provide people with information related to medical conditions. However, you can come on board for holistic treatment.


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