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Learn how you can manage Exfoliative Keratolysis


Exfoliative Keratolysis is the focal peeling of your palms and soles.

Of all the affected individuals, around 50% of cases are seen during the summer months. (1)

-Symptoms may go away on their own
-Short-term, resolves within a few days to weeks

It is characterized by local flaking of palms and in some cases feet. There is no known cause of the disease.


It is characterized by the appearance of air-filled lesions, which erupt later to reveal an underlying layer of skin. The eruptions are usually painless.
Skin can become rough and hard due to repeated recurrence.


Prevention can help avoid the symptoms, these include:
- Exposure to skin irritants and allergens
- Using lotions containing Salicylic Acid and Lactic Acid may prevent infection
- In extreme cases, Photochemotherapy may be advocated using a combination of Psoralen and Ultraviolet
- One can prevent sweating using topical agents like Drysol
- Maintaining good personal hygiene practices and avoiding exposure to the environment


Most topical agents are unable to treat exfoliative keratolysis. Initial studies have shown that administration of Soriatane shows improvement with a continual increase in the dosage.
The symptoms usually disappear on their own; however, they may soon reappear.


Exfoliative Keratolysis is usually not considered a disease of grave worry. It also does not cause any significant pain or symptoms. They may disappear on their own. However, it is best to consult your doctor to rule out any symptoms. At mfine, we provide a holistic approach to healthcare for all your medical issues. Feel free to contact us if you need any professional advice with respect your health and well-being.

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